Doctor Fomulated
Research Backed & Third Party Purity Tested
Made in the USA
Doctor Fomulated
Research Backed & Third Party Purity Tested
Made in the USA
Doctor Fomulated
Research Backed & Third Party Purity Tested
Made in the USA
  • Best Seller
    Berberine supplement by Barton Nutrition lifestyle image with headline Nature's GLP-1, showing bottle alongside key benefits for weight management, blood sugar support, and insulin sensitivity
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    Berberine supplement facts panel showing full ingredient list and dosages including 800mg berberine extract and milk thistle for enhanced bioavailability
  • Best Seller
    How to use Berberine - dosage instructions showing recommended daily serving of 2 capsules per day before meals, with suggested companion supplements CinnaChroma, TurmericBP+, and Fiber Greens
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Anyone who wants to curb cravings, support healthy weight loss, and balance blood sugar naturally — without injections or extreme diets. It boosts your body's own GLP-1 and AMPK production, which decline with age.
A clinically-studied dose of berberine extract paired with milk thistle for maximum absorption. Most berberine supplements fail because your body only absorbs about 5% — pairing it with milk thistle boosts absorption for best results.
Results compound over time, with the best benefits showing between 3-6 months. We recommend the 3 or 6-bottle bundle for lasting results and the biggest savings.
Take 1 capsule twice per day, before meals, at the same times each day.
Yes! Popular pairings include CinnaChroma for blood sugar support and Fiber Greens for gut health. Check with your healthcare provider if you're on any medications.

Berberine

Nature's GLP-1 — Without The Injections, Side Effects, Or Doctor Visits Berberine activates AMPK, your body's metabolic master switch — supporting healthy blood sugar and weight without the pharma price tag.

  • Calms post-meal blood sugar spikes Calms post-meal blood sugar spikes
  • Steadier energy without the afternoon crash Steadier energy without the afternoon crash
  • 5× absorption — most other berberine is wasted 5× absorption — most other berberine is wasted
Customer review sharing positive results with Berberine, including improved A1C and insulin levels after switching from metformin.Customer review sharing positive results with Berberine, including improved A1C and insulin levels after switching from metformin.Customer review sharing positive results with Berberine, including improved A1C and insulin levels after switching from metformin.

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  • 90 days Easy returns
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Nature’s GLP-1 — Without The Injections.
Berberine activates AMPK — your body’s metabolic master switch — for healthy blood sugar, weight, and cholesterol support.

Trusted by Thousands - Backed by Experience

From everyday meals to long-term consistency, customers report feeling more supported and confident when Berberine is part of their routine.

What Our Customers Experienced:

92.1%

Felt steadier and more balanced after meals.

91.4%

Reported healthier support for weight & metabolism.

90.7%

Felt more confident managing carbs & sugar.

93.5%

Reported better support for overall metabolic health.

Hand holding a bottle of Berberine supplement with orange flowers in the background
Dr. Scott Saunders on Berberine

Dr. Scott Saunders on Berberine

Shop Berberine

1600 mg

Clinically studied dose of Berberine shown to support blood sugar and metabolic health.

38%

Study participants showed improved insulin sensitivity and glucose metabolism when taking Berberine.

12 Weeks

In clinical research, Berberine supported healthy changes in weight, BMI, and waist circumference within 12 weeks.

Three bottles of Berberine dietary supplements on a beige background

Berberine Has Helped Thousands Of Customers Support Healthy Blood Sugar & Weight Loss – And We’re Confident It Can Work For You, Too.

For best results, we encourage consistent use over 90 days, allowing time for real, meaningful support. If you give it that time and decide it’s not for you, simply reach out within 90 days of purchase and we’ll take care of the rest.

We’re here to help you succeed, not rush a decision.

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US made
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Why Berberine?

Berberine is an advanced metabolic health supplement designed to support healthy blood sugar, weight management, and overall wellness.

Research shows berberine can help support healthy blood sugar and metabolic function – but getting enough, and absorbing it properly, can be a challenge.

That’s why we’ve combined a clinically-studied dose of berberine with milk thistle. Milk thistle helps boost berberine absorption so your body can use this powerful nutrient to its full potential.

This simple, effective formula was carefully developed by our in-house Doctor of Integrative Medicine to help you experience the powerful health benefits of berberine in your everyday life.

Three bottles of Berberine dietary supplements on a beige background

How To Use Berberine

Take 2 small capsules (one serving) daily to support metabolic health, blood sugar, and total body wellness.

How Many

How Many
2 Capsule

When

When
Take 2 capsules with your first meal of the day, preferably at the same time each day.

take together with

take together with
CinnaChroma TurmericBP+ Fiber Greens

What’s Inside Berberine?

Meet the science-backed ingredients that power Berberine and make it a favorite for those seeking better metabolic and total-body health.

Close-up of hands holding a capsule and a glass of water

Berberine is a time-tested natural compound, traditionally used to support healthy blood sugar, cholesterol, and metabolism.

Modern research shows that berberine activates AMPK – a crucial enzyme that helps your body process glucose and fat, promoting balanced blood sugar and weight management.

Our supplement includes a clinically studied dose of berberine, giving you meaningful support for healthy blood sugar, metabolism, and overall wellness.

Myths About Metabolism

  • Myth Supplements don’t help you lose weight

    Reality

    While no supplement can replace a healthy lifestyle, the right nutrients can absolutely support weight management. Berberine has been shown to help regulate blood sugar, boost metabolism, and improve insulin sensitivity, all key factors that help your body to burn fat and maintain a healthy weight.

  • Myth Metabolism slows down with age and you can’t do anything about it

    Reality

    While metabolism naturally changes as we get older, it doesn’t have to slow down. Research shows that supporting blood sugar balance, insulin sensitivity, and healthy cellular energy can keep your metabolism working efficiently. Berberine activates AMPK, often called your body’s “metabolic master switch,” helping to support a healthy metabolism at any age.

  • Myth A slow metabolism 
is genetic

    Reality

    Genetics can play a role, but they aren’t your destiny. Lifestyle choices, diet, sleep, and nutrient intake all have a huge impact on metabolism. Berberine helps address one of the most common metabolic roadblocks by supporting healthy insulin sensitivity and activating key enzymes that help your body use energy more effectively.

  • Myth You can get berberine from food sources

    Reality

    Berberine is very rare and it isn’t in any foods we eat regularly. It’s best to get berberine through a supplement that has both a clinically backed dose and a nutrient to help boost absorption, like the milk thistle ingredient in our formula.

Frequently Asked Questions

Overall rating: 4.7 / 5 from 70 reviews.

AI Generated Review Summary

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Review highlights

Reviews

"After communication with barton rep via email they explained the tumeric part of my order was out of stock. They said 4-6 weeks. I agreed to keep the order and wait. I received an email that i had a delivey coming then another that said it was delivered and it was not. Reached out to customer service and even spoke aith a supervisor Gabriel and he confirmed that i was notified incorrectly. He said that it would ve an additional 1. 5 to 2 months which is 3+ weeks from the last communication. I asked why i was not notified that the product was out of stock or why i was even allowed to order it and did not receive an answer. Only got the scripted apology and the i understand your frustration. I was offered a refund and it is supposed to be “right away”. Have I have lost confidence in Barton. I am windering if there are other issues apart from weak customer service. Sure wish that i could have spoken with someone more astute. Disappointed doesnt quite cover my experience."

— Daniel (2/5)

"I love their products, they work!! Their customer service is amazing!!"

— Y (4/5)

Great for blood sugar control

"I heard an ad on Instagram about these products. So I got the diabetes package. I was able to get off diabetic medicine and my last A1C was 5. 2. For those who don’t know what that means, my blood sugar is in the normal range."

— Cheryl S. (5/5)

"I enjoy these supplements."

— David (5/5)

Cinnachroma and berberine

"Excellent products"

— Ralph C. (5/5)

Supplemental plus

"Very pleased with this product."

— Michael H. (5/5)

An important addition to CinnaChroma!

"An important addition to CinnaChroma! This really helps with blood sugar control."

— Susan G. (5/5)

Berberine

"Works good with the CinnaChroma. I will definitely reorder as soon as I can get a good deal"

— Brenda Y. (5/5)

Yes

"In the }ast week. And 1/2 I have lost 15 more pds. My blood pressure. Is. Normal. I am 5'7 and right now I weight is. 180. I am eating keto. I will send a photo 2morrow unless Iwant ont one of me naked or of me in my gown?????"

— Katharine K. (5/5)

amazing results already

"I started taking the "Berberine" in May of this year. I am already seeing much better blood sugar numbers with this addition to my daily supplements. I am also taking the "CinnaChroma", TurmericBP+, and the "Nervala" that I purchased from your company. Thank you very much."

— Betty B. (5/5)

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